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Computational Study Reveals the Molecular Mechanism of the Interaction between the Efflux Inhibitor PAβN and the AdeB Transporter from Acinetobacter baumannii

[Image: see text] Phenylalanine-arginine β-naphthylamide (PAβN) is a broad-spectrum efflux pump inhibitor that has shown to potentiate the activity of antibiotics in Gram-negative bacteria. AdeB is a part of the AdeABC tripartite pump that plays a pivotal role in conferring efflux-mediated resistanc...

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Detalhes bibliográficos
Publicado no:ACS Omega
Main Authors: Jamshidi, Shirin, Sutton, J. Mark, Rahman, Khondaker Miraz
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2017
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6044690/
https://ncbi.nlm.nih.gov/pubmed/30023681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.7b00131
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