In silico design of sgRNAs with knockout potential for the adeB gene of the AdeABC efflux pump of Acinetobacter baumannii
Objectives: The efflux pump AdeABC, regulated by the AdeRS operon, is a key factor in multidrug resistance in Acinetobacter baumannii. The adeB gene encodes the transmembrane transporter protein, making it a promising target for therapeutic gene disruption. Methods: We designed and analyzed single g...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Elsevier
2025-09-01
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| Col·lecció: | Journal of Global Antimicrobial Resistance |
| Matèries: | |
| Accés en línia: | http://www.sciencedirect.com/science/article/pii/S2213716525001547 |
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