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In silico design of sgRNAs with knockout potential for the adeB gene of the AdeABC efflux pump of Acinetobacter baumannii

Objectives: The efflux pump AdeABC, regulated by the AdeRS operon, is a key factor in multidrug resistance in Acinetobacter baumannii. The adeB gene encodes the transmembrane transporter protein, making it a promising target for therapeutic gene disruption. Methods: We designed and analyzed single g...

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-д хадгалсан:
Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид: José Miguel Benigno Delgado Ruitón, Pedro Jorge Chimoy Effio, Guillermo Uceda Campos, Edgar Enrique Llontop Cornejo, Erick Giancarlo Suclupe Farro
Формат: Artigo
Хэл сонгох:Inglês
Хэвлэсэн: Elsevier 2025-09-01
Цуврал:Journal of Global Antimicrobial Resistance
Нөхцлүүд:
Онлайн хандалт:http://www.sciencedirect.com/science/article/pii/S2213716525001547
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