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The Asp20-to-Asn Substitution in the Response Regulator AdeR Leads to Enhanced Efflux Activity of AdeB in Acinetobacter baumannii

Overexpression of the resistance-nodulation-cell division-type efflux pump AdeABC is often associated with multidrug resistance in Acinetobacter baumannii and has been linked to mutations in the genes encoding the AdeRS two-component system. In a previous study, we reported that the Asp20→Asn amino...

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Detaylı Bibliyografya
Yayımlandı:Antimicrob Agents Chemother
Asıl Yazarlar: Nowak, Jennifer, Schneiders, Thamarai, Seifert, Harald, Higgins, Paul G.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2016
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4750716/
https://ncbi.nlm.nih.gov/pubmed/26643347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02413-15
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