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Mapping the Dynamic Functions and Structural Features of AcrB Efflux Pump Transporter Using Accelerated Molecular Dynamics Simulations

Multidrug efflux pumps confer resistance to their bacterial hosts by pumping out a diverse range of compounds, including most antibiotics. Being more familiar with the details of functional dynamics and conformations of these types of pumps could help in discovering approaches to stop them functioni...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Jamshidi, Shirin, Sutton, J. Mark, Rahman, Khondaker Miraz
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6041327/
https://ncbi.nlm.nih.gov/pubmed/29992991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-28531-6
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