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Mapping the Dynamic Functions and Structural Features of AcrB Efflux Pump Transporter Using Accelerated Molecular Dynamics Simulations

Multidrug efflux pumps confer resistance to their bacterial hosts by pumping out a diverse range of compounds, including most antibiotics. Being more familiar with the details of functional dynamics and conformations of these types of pumps could help in discovering approaches to stop them functioni...

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Jamshidi, Shirin, Sutton, J. Mark, Rahman, Khondaker Miraz
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2018
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6041327/
https://ncbi.nlm.nih.gov/pubmed/29992991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-28531-6
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