Novel Adamantanyl-Based Thiadiazolyl Pyrazoles Targeting EGFR in Triple-Negative Breast Cancer

[Image: see text] The epidermal growth factor receptor (EGFR) is a validated therapeutic target for triple-negative breast cancer (TNBC). In the present study, we synthesize novel adamantanyl-based thiadiazolyl pyrazoles by introducing the adamantane ring to thiazolopyrazoline. On the basis of loss...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:ACS Omega
Egile Nagusiak: Sebastian, Anusha, Pandey, Vijay, Mohan, Chakrabhavi Dhananjaya, Chia, Yi Ting, Rangappa, Shobith, Mathai, Jessin, Baburajeev, C. P., Paricharak, Shardul, Mervin, Lewis H., Bulusu, Krishna C., Fuchs, Julian E., Bender, Andreas, Yamada, Shuhei, Basappa, Lobie, Peter E., Rangappa, Kanchugarakoppal S.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Chemical Society 2016
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6044684/
https://ncbi.nlm.nih.gov/pubmed/30023509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.6b00251
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