A One Pot Synthesis of Novel Bioactive Tri-Substitute-Condensed-Imidazopyridines that Targets Snake Venom Phospholipase A(2)

Drugs such as necopidem, saripidem, alpidem, zolpidem, and olprinone contain nitrogen-containing bicyclic, condensed-imidazo[1,2-α]pyridines as bioactive scaffolds. In this work, we report a high-yield one pot synthesis of 1-(2-methyl-8-aryl-substitued-imidazo[1,2-α]pyridin-3-yl)ethan-1-onefor the f...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Anilkumar, Nirvanappa C., Sundaram, Mahalingam S., Mohan, Chakrabhavi Dhananjaya, Rangappa, Shobith, Bulusu, Krishna C., Fuchs, Julian E., Girish, Kesturu S., Bender, Andreas, Basappa, Rangappa, Kanchugarakoppal S.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4511007/
https://ncbi.nlm.nih.gov/pubmed/26196520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0131896
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