Epidermal growth factor receptor inhibition with Gefitinib does not alter lung responses to mechanical ventilation in fetal, preterm lambs

BACKGROUND: Epidermal growth factor receptor (EGFR) is important for airway branching and lung maturation. Mechanical ventilation of preterm lambs causes increases in EGFR and EGFR ligand mRNA in the lung. Abnormal EGFR signaling may contribute to the development of bronchopulmonary dysplasia. HYPOT...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:PLoS One
Hoofdauteurs: Kothe, T. Brett, Royse, Emily, Kemp, Matthew W., Usuda, Haruo, Saito, Masatoshi, Musk, Gabrielle C., Jobe, Alan H., Hillman, Noah H.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2018
Onderwerpen:
Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6044532/
https://ncbi.nlm.nih.gov/pubmed/30005089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0200713
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items