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Brief mechanical ventilation causes differential epithelial repair along the airways of fetal, preterm lambs

Mechanical ventilation of preterm lambs causes lung inflammation and injury to the airway epithelium, which is repaired by 15 days after ventilation. In mice, activated basal cells (p63+, KRT14+, KRT8+) initiate injury repair to the trachea, whereas club cells coordinate distal airway repair. In bot...

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Veröffentlicht in:Am J Physiol Lung Cell Mol Physiol
Hauptverfasser: Deptula, Nicole, Royse, Emily, Kemp, Matthew W., Miura, Yuichiro, Kallapur, Suhas G., Jobe, Alan H., Hillman, Noah H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5142451/
https://ncbi.nlm.nih.gov/pubmed/27343193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00181.2016
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