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Brief mechanical ventilation causes differential epithelial repair along the airways of fetal, preterm lambs

Mechanical ventilation of preterm lambs causes lung inflammation and injury to the airway epithelium, which is repaired by 15 days after ventilation. In mice, activated basal cells (p63+, KRT14+, KRT8+) initiate injury repair to the trachea, whereas club cells coordinate distal airway repair. In bot...

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Detalhes bibliográficos
Publicado no:Am J Physiol Lung Cell Mol Physiol
Main Authors: Deptula, Nicole, Royse, Emily, Kemp, Matthew W., Miura, Yuichiro, Kallapur, Suhas G., Jobe, Alan H., Hillman, Noah H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5142451/
https://ncbi.nlm.nih.gov/pubmed/27343193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00181.2016
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