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Surfactant plus budesonide decreases lung and systemic inflammation in mechanically ventilated preterm sheep

Mechanical ventilation with normal tidal volumes (V(T)) causes lung and systemic inflammation in preterm sheep. Mechanical ventilation is associated with bronchopulmonary dysplasia (BPD) in preterm infants, and the addition of budesonide to surfactant decreases BPD in clinical trials. Budesonide wit...

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Detalhes bibliográficos
Publicado no:Am J Physiol Lung Cell Mol Physiol
Main Authors: Kothe, T. Brett, Kemp, Matthew W., Schmidt, Augusto, Royse, Emily, Salomone, Fabrizio, Clarke, Michael W., Musk, Gabrielle C., Jobe, Alan H., Hillman, Noah H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6589588/
https://ncbi.nlm.nih.gov/pubmed/30838863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00477.2018
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