Simultaneous activation of innate and adaptive immunity participates in the development of renal injury in a model of heavy proteinuria

Protein overload of proximal tubular cells (PTCs) can promote interstitial injury by unclear mechanisms that may involve activation of innate immunity. We investigated whether prolonged exposure of tubular cells to high protein concentrations stimulates innate immunity, triggering progressive inters...

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Detaylı Bibliyografya
Yayımlandı:Biosci Rep
Asıl Yazarlar: Faustino, Viviane Dias, Arias, Simone Costa Alarcon, Ferreira Ávila, Victor, Foresto-Neto, Orestes, Zambom, Fernanda Florencia Fregnan, Machado, Flavia Gomes, Machado dos Reis, Luciene, Malheiros, Denise Maria Avancini Costa, Volpini, Rildo Aparecido, Camara, Niels Olsen Saraiva, Zatz, Roberto, Fujihara, Clarice Kazue
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Portland Press Ltd. 2018
Konular:
Research Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6043717/
https://ncbi.nlm.nih.gov/pubmed/29914975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20180762
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