Simultaneous activation of innate and adaptive immunity participates in the development of renal injury in a model of heavy proteinuria

Protein overload of proximal tubular cells (PTCs) can promote interstitial injury by unclear mechanisms that may involve activation of innate immunity. We investigated whether prolonged exposure of tubular cells to high protein concentrations stimulates innate immunity, triggering progressive inters...

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Библиографические подробности
Опубликовано в: :Biosci Rep
Главные авторы: Faustino, Viviane Dias, Arias, Simone Costa Alarcon, Ferreira Ávila, Victor, Foresto-Neto, Orestes, Zambom, Fernanda Florencia Fregnan, Machado, Flavia Gomes, Machado dos Reis, Luciene, Malheiros, Denise Maria Avancini Costa, Volpini, Rildo Aparecido, Camara, Niels Olsen Saraiva, Zatz, Roberto, Fujihara, Clarice Kazue
Формат: Artigo
Язык:Inglês
Опубликовано: Portland Press Ltd. 2018
Предметы:
Research Articles
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6043717/
https://ncbi.nlm.nih.gov/pubmed/29914975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20180762
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