iTAP, a novel iRhom interactor, controls TNF secretion by policing the stability of iRhom/TACE

The apical inflammatory cytokine TNF regulates numerous important biological processes including inflammation and cell death, and drives inflammatory diseases. TNF secretion requires TACE (also called ADAM17), which cleaves TNF from its transmembrane tether. The trafficking of TACE to the cell surfa...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:eLife
Egile Nagusiak: Oikonomidi, Ioanna, Burbridge, Emma, Cavadas, Miguel, Sullivan, Graeme, Collis, Blanka, Naegele, Heike, Clancy, Danielle, Brezinova, Jana, Hu, Tianyi, Bileck, Andrea, Gerner, Christopher, Bolado, Alfonso, von Kriegsheim, Alex, Martin, Seamus J, Steinberg, Florian, Strisovsky, Kvido, Adrain, Colin
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: eLife Sciences Publications, Ltd 2018
Gaiak:
Biochemistry and Chemical Biology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6042963/
https://ncbi.nlm.nih.gov/pubmed/29897333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.35032
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak