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Computational Approaches to Identify Genetic Interactions for Cancer Therapeutics

The development of improved cancer therapies is frequently cited as an urgent unmet medical need. Here we describe how genetic interactions are being therapeutically exploited to identify novel targeted treatments for cancer. We discuss the current methodologies that use ‘omics data to identify gene...

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Pubblicato in:J Integr Bioinform
Autori principali: Benstead-Hume, Graeme, Wooller, Sarah K., Pearl, Frances M.G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: De Gruyter 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6042820/
https://ncbi.nlm.nih.gov/pubmed/28941356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1515/jib-2017-0027
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