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Computational Approaches to Identify Genetic Interactions for Cancer Therapeutics

The development of improved cancer therapies is frequently cited as an urgent unmet medical need. Here we describe how genetic interactions are being therapeutically exploited to identify novel targeted treatments for cancer. We discuss the current methodologies that use ‘omics data to identify gene...

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發表在:J Integr Bioinform
Main Authors: Benstead-Hume, Graeme, Wooller, Sarah K., Pearl, Frances M.G.
格式: Artigo
語言:Inglês
出版: De Gruyter 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6042820/
https://ncbi.nlm.nih.gov/pubmed/28941356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1515/jib-2017-0027
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