Computational approaches to identify functional genetic variants in cancer genomes

The International Cancer Genome Consortium (ICGC) aims to catalog genomic abnormalities in tumors from 50 different cancer types. Genome sequencing reveals hundreds to thousands of somatic mutations in each tumor, but only a minority drive tumor progression. We present the result of discussions with...

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Main Authors: Gonzalez-Perez, Abel, Mustonen, Ville, Reva, Boris, Ritchie, Graham R.S., Creixell, Pau, Karchin, Rachel, Vazquez, Miguel, Fink, J. Lynn, Kassahn, Karin S., Pearson, John V., Bader, Gary, Boutros, Paul C., Muthuswamy, Lakshmi, Ouellette, B.F. Francis, Reimand, Jüri, Linding, Rune, Shibata, Tatsuhiro, Valencia, Alfonso, Butler, Adam, Dronov, Serge, Flicek, Paul, Shannon, Nick B., Carter, Hannah, Ding, Li, Sander, Chris, Stuart, Josh M., Stein, Lincoln D., Lopez-Bigas, Nuria
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2013
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3919555/
https://ncbi.nlm.nih.gov/pubmed/23900255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.2562
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