Computational approaches to identify functional genetic variants in cancer genomes

The International Cancer Genome Consortium (ICGC) aims to catalog genomic abnormalities in tumors from 50 different cancer types. Genome sequencing reveals hundreds to thousands of somatic mutations in each tumor, but only a minority drive tumor progression. We present the result of discussions with...

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Detalhes bibliográficos
Main Authors: Gonzalez-Perez, Abel, Mustonen, Ville, Reva, Boris, Ritchie, Graham R.S., Creixell, Pau, Karchin, Rachel, Vazquez, Miguel, Fink, J. Lynn, Kassahn, Karin S., Pearson, John V., Bader, Gary, Boutros, Paul C., Muthuswamy, Lakshmi, Ouellette, B.F. Francis, Reimand, Jüri, Linding, Rune, Shibata, Tatsuhiro, Valencia, Alfonso, Butler, Adam, Dronov, Serge, Flicek, Paul, Shannon, Nick B., Carter, Hannah, Ding, Li, Sander, Chris, Stuart, Josh M., Stein, Lincoln D., Lopez-Bigas, Nuria
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3919555/
https://ncbi.nlm.nih.gov/pubmed/23900255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.2562
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