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Identification and analysis of mutational hotspots in oncogenes and tumour suppressors

BACKGROUND: The key to interpreting the contribution of a disease-associated mutation in the development and progression of cancer is an understanding of the consequences of that mutation both on the function of the affected protein and on the pathways in which that protein is involved. Protein doma...

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Publicat a:Oncotarget
Autors principals: Baeissa, Hanadi, Benstead-Hume, Graeme, Richardson, Christopher J., Pearl, Frances M.G
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5400584/
https://ncbi.nlm.nih.gov/pubmed/28423505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.15514
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