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Wilms’ tumours: about tumour suppressor genes, an oncogene and a chameleon gene
Genes identified as being mutated in Wilms’ tumour include TP53, a classic tumour suppressor gene (TSG); CTNNB1 (encoding β-catenin), a classic oncogene; WTX, which accumulating data indicate is a TSG; and WT1, which is inactivated in some Wilms’ tumours, similar to a TSG. However, WT1 does not alwa...
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| Publicado no: | Nat Rev Cancer |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4332715/ https://ncbi.nlm.nih.gov/pubmed/21248786 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrc3002 |
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