Optimal vitamin D spurs serotonin: 1,25-dihydroxyvitamin D represses serotonin reuptake transport (SERT) and degradation (MAO-A) gene expression in cultured rat serotonergic neuronal cell lines

BACKGROUND: Diminished brain levels of two neurohormones, 5-hydroxytryptamine (5-HT; serotonin) and 1,25-dihydroxyvitamin D(3) (1,25D; active vitamin D metabolite), are proposed to play a role in the atypical social behaviors associated with psychological conditions including autism spectrum disorde...

Full description

Saved in:
Bibliographic Details
Published in:Genes Nutr
Main Authors: Sabir, Marya S., Haussler, Mark R., Mallick, Sanchita, Kaneko, Ichiro, Lucas, Daniel A., Haussler, Carol A., Whitfield, G. Kerr, Jurutka, Peter W.
Format: Artigo
Language:Inglês
Published: BioMed Central 2018
Subjects:
Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6042449/
https://ncbi.nlm.nih.gov/pubmed/30008960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12263-018-0605-7
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items