STK25-induced inhibition of aerobic glycolysis via GOLPH3-mTOR pathway suppresses cell proliferation in colorectal cancer

BACKGROUND: Serine/threonine protein kinase 25 (STK25) is critical in regulating whole-body glucose and insulin homeostasis and the accumulation of ectopic lipids. The Warburg effect, also known as aerobic glycolysis, is an essential metabolic characteristic of cancer cells. However, the effects of...

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Detalhes bibliográficos
Publicado no:J Exp Clin Cancer Res
Main Authors: Wu, Fan, Gao, Pin, Wu, Wei, Wang, Zaozao, Yang, Jie, Di, Jiabo, Jiang, Beihai, Su, Xiangqian
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6042396/
https://ncbi.nlm.nih.gov/pubmed/29996891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-018-0808-1
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