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CENPH Inhibits Rapamycin Sensitivity by Regulating GOLPH3-dependent mTOR Signaling Pathway in Colorectal Cancer

Background: Centromere protein H (CENPH) is known as a fundamental component of the active centromere complex, and its overexpression is correlated with poor prognosis in various solid tumors. mTOR inhibitor rapamycin has been shown to possess antitumor activity, as well as prevent intestinal tumori...

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Detalhes bibliográficos
Publicado no:J Cancer
Main Authors: Wu, Wei, Wu, Fan, Wang, Zaozao, Di, Jiabo, Yang, Jie, Gao, Pin, Jiang, Beihai, Su, Xiangqian
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5560133/
https://ncbi.nlm.nih.gov/pubmed/28819418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.19940
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