Decreased Expression of MPC2 Contributes to Aerobic Glycolysis and Colorectal Cancer Proliferation by Activating mTOR Pathway

Mitochondrial Pyruvate Carrier 1 (MPC1), one of the rate-limiting proteins involved in glycolysis metabolism, has been demonstrated as a tumor inhibitor in several cancers. This study was conducted with the aim of exploring the role and underlying mechanisms of MPC2 in colorectal cancer (CRC). Here,...

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Udgivet i:J Immunol Res
Main Authors: Kuerbanjiang, Manzila, Gu, Lei, Xu, Chunjie, Xu, Wen Ting, Wen, Siyuan, Xue, Hanbing, Xu, Qing
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi 2021
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7984920/
https://ncbi.nlm.nih.gov/pubmed/33791391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2021/6618837
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