Alternative DNA secondary structure formation affects RNA polymerase II promoter-proximal pausing in human

BACKGROUND: Alternative DNA secondary structures can arise from single-stranded DNA when duplex DNA is unwound during DNA processes such as transcription, resulting in the regulation or perturbation of these processes. We identify sites of high propensity to form stable DNA secondary structure acros...

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Publicado en:Genome Biol
Autores principales: Szlachta, Karol, Thys, Ryan G., Atkin, Naomi D., Pierce, Levi C. T., Bekiranov, Stefan, Wang, Yuh-Hwa
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2018
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Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6042338/
https://ncbi.nlm.nih.gov/pubmed/30001206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-018-1463-8
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