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Staphylococcus aureus targets the purine salvage pathway to kill phagocytes
Staphylococcus aureus colonizes large segments of the human population and causes invasive infections due to its ability to escape phagocytic clearance. During infection, staphylococcal nuclease and adenosine synthase A convert neutrophil extracellular traps to deoxyadenosine (dAdo), which kills pha...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6042115/ https://ncbi.nlm.nih.gov/pubmed/29891696 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1805622115 |
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