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Staphylococcus aureus targets the purine salvage pathway to kill phagocytes
Staphylococcus aureus colonizes large segments of the human population and causes invasive infections due to its ability to escape phagocytic clearance. During infection, staphylococcal nuclease and adenosine synthase A convert neutrophil extracellular traps to deoxyadenosine (dAdo), which kills pha...
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| Published in: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
2018
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6042115/ https://ncbi.nlm.nih.gov/pubmed/29891696 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1805622115 |
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