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Staphylococcus aureus targets the purine salvage pathway to kill phagocytes

Staphylococcus aureus colonizes large segments of the human population and causes invasive infections due to its ability to escape phagocytic clearance. During infection, staphylococcal nuclease and adenosine synthase A convert neutrophil extracellular traps to deoxyadenosine (dAdo), which kills pha...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Winstel, Volker, Missiakas, Dominique, Schneewind, Olaf
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6042115/
https://ncbi.nlm.nih.gov/pubmed/29891696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1805622115
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