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VSV-G-Enveloped Vesicles for Traceless Delivery of CRISPR-Cas9
The method of delivery of CRISPR-Cas9 into target cells is a strong determinant of efficacy and specificity in genome editing. Even though high efficiency of Cas9 delivery is necessary for optimal editing, its long-term and high levels of expression correlate with increased off-target activity. We d...
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| Pubblicato in: | Mol Ther Nucleic Acids |
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| Autori principali: | , , , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society of Gene & Cell Therapy
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6041463/ https://ncbi.nlm.nih.gov/pubmed/30195783 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2018.05.010 |
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