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CRISPR-Csy4-Mediated Editing of Rotavirus Double-Stranded RNA Genome
CRISPR-nucleases have been widely applied for editing cellular and viral genomes, but nuclease-mediated genome editing of double-stranded RNA (dsRNA) viruses has not yet been reported. Here, by engineering CRISPR-Csy4 nuclease to localize to rotavirus viral factories, we achieve the nuclease-mediate...
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| Publicado no: | Cell Rep |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Authors.
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7523552/ https://ncbi.nlm.nih.gov/pubmed/32997981 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.108205 |
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