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CRISPR-Cap: multiplexed double-stranded DNA enrichment based on the CRISPR system

Existing methods to enrich target regions of genomic DNA based on PCR, hybridization capture, or molecular inversion probes have various drawbacks, including long experiment times and low throughput and/or enrichment quality. We developed CRISPR-Cap, a simple and scalable CRISPR-based method to enri...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nucleic Acids Res
Prif Awduron: Lee, Jeewon, Lim, Hyeonseob, Jang, Hoon, Hwang, Byungjin, Lee, Joon Ho, Cho, Junhyuk, Lee, Ji Hyun, Bang, Duhee
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6326800/
https://ncbi.nlm.nih.gov/pubmed/30215766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky820
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