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Insulin Hexamer Dissociation Dynamics Revealed by Photoinduced T-jumps and Time-Resolved X-Ray Solution Scattering

The structural dynamics of Insulin hexamer dissociation were studied by the photoinduced temperature jump technique and monitored by time-resolved x-ray scattering. The process of hexamer dissociation was found to involve several transient intermediates, including an expanded hexamer and an unstable...

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Detalhes bibliográficos
Publicado no:Photochem Photobiol Sci
Main Authors: Rimmerman, Dolev, Leshchev, Denis, Hsu, Darren J., Hong, Jiyun, Abraham, Baxter, Kosheleva, Irina, Henning, Robert, Chen, Lin X.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6041135/
https://ncbi.nlm.nih.gov/pubmed/29855030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8pp00034d
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