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Direct Observation of Insulin Association Dynamics with Time-Resolved X-ray Scattering
Biological functions frequently require protein–protein interactions that involve secondary and tertiary structural perturbation. Here we study protein–protein dissociation and reassociation dynamics in insulin, a model system for protein oligomerization. Insulin dimer dissociation into monomers was...
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| Izdano u: | J Phys Chem Lett |
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| Glavni autori: | , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2017
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5804350/ https://ncbi.nlm.nih.gov/pubmed/28853898 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpclett.7b01720 |
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