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X-ray snapshots reveal conformational influence on active site ligation during metalloprotein folding

Cytochrome c (cyt c) has long been utilized as a model system to study metalloprotein folding dynamics and the interplay between active site ligation and tertiary structure. However, recent reports regarding the weakness of the native Fe(ii)–S bond (Fe–Met80) call into question the role of the activ...

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Detalhes bibliográficos
Publicado no:Chem Sci
Main Authors: Hsu, Darren J., Leshchev, Denis, Rimmerman, Dolev, Hong, Jiyun, Kelley, Matthew S., Kosheleva, Irina, Zhang, Xiaoyi, Chen, Lin X.
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6993610/
https://ncbi.nlm.nih.gov/pubmed/32055348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9sc02630d
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