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X-ray snapshots reveal conformational influence on active site ligation during metalloprotein folding

Cytochrome c (cyt c) has long been utilized as a model system to study metalloprotein folding dynamics and the interplay between active site ligation and tertiary structure. However, recent reports regarding the weakness of the native Fe(ii)–S bond (Fe–Met80) call into question the role of the activ...

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Vydáno v:Chem Sci
Hlavní autoři: Hsu, Darren J., Leshchev, Denis, Rimmerman, Dolev, Hong, Jiyun, Kelley, Matthew S., Kosheleva, Irina, Zhang, Xiaoyi, Chen, Lin X.
Médium: Artigo
Jazyk:Inglês
Vydáno: Royal Society of Chemistry 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6993610/
https://ncbi.nlm.nih.gov/pubmed/32055348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9sc02630d
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