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X-ray snapshots reveal conformational influence on active site ligation during metalloprotein folding

Cytochrome c (cyt c) has long been utilized as a model system to study metalloprotein folding dynamics and the interplay between active site ligation and tertiary structure. However, recent reports regarding the weakness of the native Fe(ii)–S bond (Fe–Met80) call into question the role of the activ...

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Bibliografische gegevens
Gepubliceerd in:Chem Sci
Hoofdauteurs: Hsu, Darren J., Leshchev, Denis, Rimmerman, Dolev, Hong, Jiyun, Kelley, Matthew S., Kosheleva, Irina, Zhang, Xiaoyi, Chen, Lin X.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Royal Society of Chemistry 2019
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6993610/
https://ncbi.nlm.nih.gov/pubmed/32055348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9sc02630d
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