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X-ray snapshots reveal conformational influence on active site ligation during metalloprotein folding

Cytochrome c (cyt c) has long been utilized as a model system to study metalloprotein folding dynamics and the interplay between active site ligation and tertiary structure. However, recent reports regarding the weakness of the native Fe(ii)–S bond (Fe–Met80) call into question the role of the activ...

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Dades bibliogràfiques
Publicat a:Chem Sci
Autors principals: Hsu, Darren J., Leshchev, Denis, Rimmerman, Dolev, Hong, Jiyun, Kelley, Matthew S., Kosheleva, Irina, Zhang, Xiaoyi, Chen, Lin X.
Format: Artigo
Idioma:Inglês
Publicat: Royal Society of Chemistry 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6993610/
https://ncbi.nlm.nih.gov/pubmed/32055348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9sc02630d
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