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Tenectin recruits integrin to stabilize bouton architecture and regulate vesicle release at the Drosophila neuromuscular junction

Assembly, maintenance and function of synaptic junctions depend on extracellular matrix (ECM) proteins and their receptors. Here we report that Tenectin (Tnc), a Mucin-type protein with RGD motifs, is an ECM component required for the structural and functional integrity of synaptic specializations a...

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Bibliografische gegevens
Gepubliceerd in:eLife
Hoofdauteurs: Wang, Qi, Han, Tae Hee, Nguyen, Peter, Jarnik, Michal, Serpe, Mihaela
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: eLife Sciences Publications, Ltd 2018
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6040883/
https://ncbi.nlm.nih.gov/pubmed/29901439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.35518
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