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Tenectin recruits integrin to stabilize bouton architecture and regulate vesicle release at the Drosophila neuromuscular junction

Assembly, maintenance and function of synaptic junctions depend on extracellular matrix (ECM) proteins and their receptors. Here we report that Tenectin (Tnc), a Mucin-type protein with RGD motifs, is an ECM component required for the structural and functional integrity of synaptic specializations a...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Wang, Qi, Han, Tae Hee, Nguyen, Peter, Jarnik, Michal, Serpe, Mihaela
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6040883/
https://ncbi.nlm.nih.gov/pubmed/29901439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.35518
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