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Tenectin recruits integrin to stabilize bouton architecture and regulate vesicle release at the Drosophila neuromuscular junction

Assembly, maintenance and function of synaptic junctions depend on extracellular matrix (ECM) proteins and their receptors. Here we report that Tenectin (Tnc), a Mucin-type protein with RGD motifs, is an ECM component required for the structural and functional integrity of synaptic specializations a...

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Detalles Bibliográficos
Publicado en:eLife
Main Authors: Wang, Qi, Han, Tae Hee, Nguyen, Peter, Jarnik, Michal, Serpe, Mihaela
Formato: Artigo
Idioma:Inglês
Publicado: eLife Sciences Publications, Ltd 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6040883/
https://ncbi.nlm.nih.gov/pubmed/29901439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.35518
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