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Lewis Acid Activation of the Ferrous Heme–NO Fragment Towards the N–N Coupling Reaction with NO to Generate N(2)O

Bacterial NO reductase (bacNOR) enzymes utilize a heme-nonheme active site to couple two NO molecules to N(2)O. We show that BF(3) coordination to the nitrosyl O-atom in (OEP)Fe(NO) activates it towards N–N bond formation with NO to generate N(2)O. (15)N-isotopic labeling reveals a reversible nitros...

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Bibliografiske detaljer
Udgivet i:J Am Chem Soc
Main Authors: Abucayon, Erwin G., Khade, Rahul L., Powell, Douglas R., Zhang, Yong, Richter-Addo, George B.
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6040813/
https://ncbi.nlm.nih.gov/pubmed/29502400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.7b13681
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