A speed–fidelity trade-off determines the mutation rate and virulence of an RNA virus

Mutation rates can evolve through genetic drift, indirect selection due to genetic hitchhiking, or direct selection on the physicochemical cost of high fidelity. However, for many systems, it has been difficult to disentangle the relative impact of these forces empirically. In RNA viruses, an observ...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PLoS Biol
Prif Awduron: Fitzsimmons, William J., Woods, Robert J., McCrone, John T., Woodman, Andrew, Arnold, Jamie J., Yennawar, Madhumita, Evans, Richard, Cameron, Craig E., Lauring, Adam S.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2018
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6040757/
https://ncbi.nlm.nih.gov/pubmed/29953453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.2006459
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