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Sensitivity of breast cancer cell lines to recombinant thiaminase I

PURPOSE: We have previously shown that the expression of the thiamine transporter THTR2 is decreased sevenfold in breast cancer, which may leave breast cancer cells vulnerable to acute thiamine starvation. This concept was supported by the observation that MDA231 breast cancer xenografts demonstrate...

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Détails bibliographiques
Publié dans:Cancer Chemother Pharmacol
Auteurs principaux: Liu, Shuqian, Monks, Noel R., Hanes, Jeremiah W., Begley, Tadhg P., Yu, Hui, Moscow, Jeffrey A.
Format: Artigo
Langue:Inglês
Publié: 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6040657/
https://ncbi.nlm.nih.gov/pubmed/19830429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-009-1148-9
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