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Sensitivity of breast cancer cell lines to recombinant thiaminase I

PURPOSE: We have previously shown that the expression of the thiamine transporter THTR2 is decreased sevenfold in breast cancer, which may leave breast cancer cells vulnerable to acute thiamine starvation. This concept was supported by the observation that MDA231 breast cancer xenografts demonstrate...

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Bibliografische gegevens
Gepubliceerd in:Cancer Chemother Pharmacol
Hoofdauteurs: Liu, Shuqian, Monks, Noel R., Hanes, Jeremiah W., Begley, Tadhg P., Yu, Hui, Moscow, Jeffrey A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2009
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6040657/
https://ncbi.nlm.nih.gov/pubmed/19830429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-009-1148-9
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