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Sensitivity of breast cancer cell lines to recombinant thiaminase I

PURPOSE: We have previously shown that the expression of the thiamine transporter THTR2 is decreased sevenfold in breast cancer, which may leave breast cancer cells vulnerable to acute thiamine starvation. This concept was supported by the observation that MDA231 breast cancer xenografts demonstrate...

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Detalhes bibliográficos
Publicado no:Cancer Chemother Pharmacol
Main Authors: Liu, Shuqian, Monks, Noel R., Hanes, Jeremiah W., Begley, Tadhg P., Yu, Hui, Moscow, Jeffrey A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6040657/
https://ncbi.nlm.nih.gov/pubmed/19830429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-009-1148-9
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