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Sensitivity of breast cancer cell lines to recombinant thiaminase I

PURPOSE: We have previously shown that the expression of the thiamine transporter THTR2 is decreased sevenfold in breast cancer, which may leave breast cancer cells vulnerable to acute thiamine starvation. This concept was supported by the observation that MDA231 breast cancer xenografts demonstrate...

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書目詳細資料
發表在:Cancer Chemother Pharmacol
Main Authors: Liu, Shuqian, Monks, Noel R., Hanes, Jeremiah W., Begley, Tadhg P., Yu, Hui, Moscow, Jeffrey A.
格式: Artigo
語言:Inglês
出版: 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6040657/
https://ncbi.nlm.nih.gov/pubmed/19830429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-009-1148-9
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