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Sensitivity of breast cancer cell lines to recombinant thiaminase I

PURPOSE: We have previously shown that the expression of the thiamine transporter THTR2 is decreased sevenfold in breast cancer, which may leave breast cancer cells vulnerable to acute thiamine starvation. This concept was supported by the observation that MDA231 breast cancer xenografts demonstrate...

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Библиографические подробности
Опубликовано в: :Cancer Chemother Pharmacol
Главные авторы: Liu, Shuqian, Monks, Noel R., Hanes, Jeremiah W., Begley, Tadhg P., Yu, Hui, Moscow, Jeffrey A.
Формат: Artigo
Язык:Inglês
Опубликовано: 2009
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6040657/
https://ncbi.nlm.nih.gov/pubmed/19830429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-009-1148-9
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