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Msp1 is a membrane protein dislocase for tail-anchored proteins

Mislocalized tail-anchored (TA) proteins of the outer mitochondrial membrane are cleared by a newly identified quality control pathway involving the conserved eukaryotic protein Msp1 (ATAD1 in humans). Msp1 is a transmembrane AAA-ATPase but its role in TA protein clearance is not known. Here, using...

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Publicat a:Mol Cell
Autors principals: Wohlever, Matthew L., Mateja, Agnieszka, McGilvray, Philip T., Day, Kasey J., Keenan, Robert J.
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6040593/
https://ncbi.nlm.nih.gov/pubmed/28712723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2017.06.019
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