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An allelic variant in the intergenic region between ERAP1 and ERAP2 correlates with an inverse expression of the two genes

The Endoplasmatic Reticulum Aminopeptidases ERAP1 and ERAP2 are implicated in a variety of immune and non-immune functions. Most studies however have focused on their role in shaping the HLA class I peptidome by trimming peptides to the optimal size. Genome Wide Association Studies highlighted non-s...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Paladini, Fabiana, Fiorillo, Maria Teresa, Vitulano, Carolina, Tedeschi, Valentina, Piga, Matteo, Cauli, Alberto, Mathieu, Alessandro, Sorrentino, Rosa
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6039459/
https://ncbi.nlm.nih.gov/pubmed/29991817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-28799-8
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