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The Multifaceted Nature of Aminopeptidases ERAP1, ERAP2, and LNPEP: From Evolution to Disease

In the human genome, the aminopeptidases ERAP1, ERAP2 and LNPEP lie contiguously on chromosome 5. They share sequence homology, functions and associations with immune-mediated diseases. By analyzing their multifaceted activities as well as their expression in the zoological scale, we suggest here th...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Paladini, Fabiana, Fiorillo, Maria Teresa, Tedeschi, Valentina, Mattorre, Benedetta, Sorrentino, Rosa
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7390905/
https://ncbi.nlm.nih.gov/pubmed/32793222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.01576
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