Ankylosing Spondylitis: A Trade Off of HLA-B27, ERAP, and Pathogen Interconnections? Focus on Sardinia

The frequency of HLA-B27 in patients with Ankylosing Spondylitis (AS) is over 85%. There are more than 170 recognized HLA-B27 alleles but the majority of them is not sufficiently represented for genetic association studies. So far only two alleles, the HLA-B(*)2706 in Asia and the HLA-B(*)2709 in Sa...

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Bibliographische Detailangaben
Veröffentlicht in:Front Immunol
Hauptverfasser: Paladini, Fabiana, Fiorillo, Maria Teresa, Tedeschi, Valentina, Cauli, Alberto, Mathieu, Alessandro, Sorrentino, Rosa
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2019
Schlagworte:
Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6355666/
https://ncbi.nlm.nih.gov/pubmed/30740100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.00035
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