The Ankylosing Spondylitis-Associated HLA-B*2705 Presents a B*0702-Restricted EBV Epitope and Sustains the Clonal Amplification of Cytotoxic T Cells in Patients

HLA-B*27 is strongly associated with an inflammatory autoimmune disorder, the Ankylosing Spondylitis (AS) and plays a protective role in viral infections. The two aspects might be linked. In this work, we compared in B*2705/B*07 positive patients with AS, the CD8(+) T cell responses to two immunodom...

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Udgivet i:Mol Med
Main Authors: Tedeschi, Valentina, Vitulano, Carolina, Cauli, Alberto, Paladini, Fabiana, Piga, Matteo, Mathieu, Alessandro, Sorrentino, Rosa, Fiorillo, Maria Teresa
Format: Artigo
Sprog:Inglês
Udgivet: Feinstein Institute for Medical Research 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5004723/
https://ncbi.nlm.nih.gov/pubmed/27254288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2016.00031
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