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CDK4/6 inhibitors: The mechanism of action may not be as simple as once thought

CDK4/6 inhibitors are among a new generation of therapeutics. Building upon the striking success of the combination of CDK4/6 inhibitors and the hormone receptor antagonist letrozole in breast cancer, many other combinations have recently entered clinical trials in multiple diseases. To achieve maxi...

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Detalhes bibliográficos
Publicado no:Cancer Cell
Main Authors: Klein, Mary E., Kovatcheva, Marta, Davis, Lara E., Tap, William D., Koff, Andrew
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6039233/
https://ncbi.nlm.nih.gov/pubmed/29731395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2018.03.023
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