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Assaying Repair at DNA Nicks

Nicks are the most common form of DNA damage, but they have only recently been shown to initiate damage that requires repair. Analysis of the pathways of nick repair in human cells has benefited from the development of enzymes that target nicks to specific sites in the genome and of reporters that e...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Methods Enzymol
Hauptverfasser: Davis, Luther, Zhang, Yinbo, Maizels, Nancy
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6039113/
https://ncbi.nlm.nih.gov/pubmed/29523243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.mie.2017.12.001
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