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Inflammation-induced DNA methylation of DNA polymerase gamma alters the metabolic profile of colon tumors

BACKGROUND: Inflammation, metabolism, and epigenetic modulation are highly interconnected processes that can be altered during tumorigenesis. However, because of the complexity of these interactions, direct cause and effect during tumorigenesis have been difficult to prove. Previously, using a murin...

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Publicado en:Cancer Metab
Main Authors: Maiuri, Ashley R., Li, Hongde, Stein, Barry D., Tennessen, Jason M., O’Hagan, Heather M.
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6038244/
https://ncbi.nlm.nih.gov/pubmed/30002826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40170-018-0182-7
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