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Inflammation-induced DNA methylation of DNA polymerase gamma alters the metabolic profile of colon tumors

BACKGROUND: Inflammation, metabolism, and epigenetic modulation are highly interconnected processes that can be altered during tumorigenesis. However, because of the complexity of these interactions, direct cause and effect during tumorigenesis have been difficult to prove. Previously, using a murin...

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Библиографические подробности
Опубликовано в: :Cancer Metab
Главные авторы: Maiuri, Ashley R., Li, Hongde, Stein, Barry D., Tennessen, Jason M., O’Hagan, Heather M.
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2018
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6038244/
https://ncbi.nlm.nih.gov/pubmed/30002826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40170-018-0182-7
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